Clinical usefulness of high resolution computed tomography in cryptogenic fibrosing alveolitis

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Clinical usefulness of high resolution computed tomography in cryptogenic fibrosing alveolitis.

Despite recent technological advances, agreement amongst clinicians on an algorithm for the optimal management of cryptogenic fibrosing alveolitis (CFA) has proved to be elusive. The non-invasive diagnosis of CFA is often uncertain as the clinical features may mimic those of other interstitial lung diseases. Even when the diagnosis is secure, therapeutic decisions are not straightforward. Rever...

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High resolution computed tomographic assessment of asbestosis and cryptogenic fibrosing alveolitis: a comparative study.

BACKGROUND The aim of this study was to compare the distribution and configuration of lung opacities in patients with cryptogenic fibrosing alveolitis and asbestosis by high resolution computed tomography. METHODS Eighteen patients with cryptogenic fibrosing alveolitis and 24 with asbestosis were studied. Two independent observers assessed the type and distributions of opacities in the upper,...

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Cryptogenic fibrosing alveolitis and the fibrosing alveolitis of systemic sclerosis: morphological differences on computed tomographic scans.

BACKGROUND The purpose of this study was to identify morphological differences on the computed tomographic (CT) scan between cryptogenic fibrosing alveolitis (CFA) and the fibrosing alveolitis associated with systemic sclerosis (FASSc), and to examine their biological relevance. METHODS One hundred and seven patients with CFA (n = 55) or FASSc (n = 52) who had undergone thin section CT scanni...

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Autoantibodies in cryptogenic fibrosing alveolitis

The pathogenesis of cryptogenic fibrosing alveolitis (CFA) involves injury, an immune/inflammatory response and fibrosis. The cause of the injury is unknown, but the identification of serum autoantibodies makes an autoimmune aetiology attractive. The core study on which this commentary is based used novel cloning and serum screening technologies in order to identify new public and private autoa...

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Prognosis of cryptogenic fibrosing alveolitis.

We have analysed retrospectively 100 consecutive patients with cryptogenic fibrosing alveolitis, who were treated with corticosteroids and followed for at least three years. At the time of diagnosis biopsy specimens were available in 64 cases. The clinical, radiographic, physiological, and histological features and the response to steroid treatment have been correlated with the prognosis. An ea...

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ژورنال

عنوان ژورنال: Thorax

سال: 1998

ISSN: 0040-6376

DOI: 10.1136/thx.53.12.1080